What is the difference between Compounded Semaglutide, Compounded Tirzepatide, and Wegovy?

Compounded Semaglutide (semaglutide (compounded)), Compounded Tirzepatide (tirzepatide (compounded)), and Wegovy (semaglutide) are GLP-1 medications used for weight management or type 2 diabetes. Key differences: Compounded Semaglutide is compounded, Compounded Tirzepatide is compounded, Wegovy is FDA-approved.

Which is most effective for weight loss: Compounded Semaglutide, Compounded Tirzepatide, or Wegovy?

Effectiveness varies by individual. In clinical trials, tirzepatide-based drugs (Mounjaro, Zepbound) produced ~22% average body-weight loss vs ~15% for semaglutide-based (Ozempic, Wegovy). Discuss with your prescriber.

Cash retail price: Compounded Semaglutide $250/mo · Compounded Tirzepatide $299/mo · Wegovy $1349/mo. Compounded versions through telehealth typically run 60-80% less.

3-way comparison

Compounded Semaglutide vs Compounded Tirzepatide vs Wegovy

Side-by-side breakdown — efficacy, cost, regulatory status, and who each option fits best.

Compounded Semaglutide

semaglutide (compounded)

Compounded Tirzepatide

tirzepatide (compounded)

Wegovy

semaglutide

Side-by-side comparison

Attribute	Compounded Semaglutide	Compounded Tirzepatide	Wegovy
Generic name	semaglutide (compounded)	tirzepatide (compounded)	semaglutide
Drug class	—	—	—
Regulatory status	Compounded	Compounded	FDA approved
Manufacturer	Various compounding pharmacies	Various compounding pharmacies	Novo Nordisk
Avg retail price	$250/mo	$299/mo	$1349/mo
Without insurance	$99–$350/mo	$149–$399/mo	$1349–$1500/mo
Savings card max	$0/mo	$0/mo	$0/mo

Compounded Semaglutide vs Compounded Tirzepatide vs Wegovy

Side-by-side comparison

FAQ

2-way head-to-heads

Already on one? Switching guides

None feel right? See alternatives