What is the difference between Mounjaro, Ozempic, and Saxenda?

Mounjaro (tirzepatide), Ozempic (semaglutide), and Saxenda (liraglutide) are GLP-1 medications used for weight management or type 2 diabetes. Key differences: Mounjaro is FDA-approved, Ozempic is FDA-approved, Saxenda is FDA-approved.

Which is most effective for weight loss: Mounjaro, Ozempic, or Saxenda?

Effectiveness varies by individual. In clinical trials, tirzepatide-based drugs (Mounjaro, Zepbound) produced ~22% average body-weight loss vs ~15% for semaglutide-based (Ozempic, Wegovy). Discuss with your prescriber.

Cash retail price: Ozempic $968/mo · Mounjaro $1135/mo · Saxenda $1349/mo. Compounded versions through telehealth typically run 60-80% less.

3-way comparison

Mounjaro vs Ozempic vs Saxenda

Side-by-side breakdown — efficacy, cost, regulatory status, and who each option fits best.

Mounjaro

tirzepatide

Ozempic

semaglutide

Saxenda

liraglutide

Side-by-side comparison

Attribute	Mounjaro	Ozempic	Saxenda
Generic name	tirzepatide	semaglutide	liraglutide
Drug class	—	—	—
Regulatory status	FDA approved	FDA approved	FDA approved
Manufacturer	Eli Lilly	Novo Nordisk	Novo Nordisk
Avg retail price	$1135/mo	$968/mo	$1349/mo
Without insurance	$1023–$1330/mo	$968–$1100/mo	$1100–$1500/mo
Savings card max	$25/mo	$25/mo	$25/mo
Shortage status

Mounjaro vs Ozempic vs Saxenda

Side-by-side comparison

FAQ

2-way head-to-heads

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