What is the difference between Mounjaro, Zepbound, and Compounded Tirzepatide?

Mounjaro (tirzepatide), Zepbound (tirzepatide), and Compounded Tirzepatide (tirzepatide (compounded)) are GLP-1 medications used for weight management or type 2 diabetes. Key differences: Mounjaro is FDA-approved, Zepbound is FDA-approved, Compounded Tirzepatide is compounded.

Which is most effective for weight loss: Mounjaro, Zepbound, or Compounded Tirzepatide?

Effectiveness varies by individual. In clinical trials, tirzepatide-based drugs (Mounjaro, Zepbound) produced ~22% average body-weight loss vs ~15% for semaglutide-based (Ozempic, Wegovy). Discuss with your prescriber.

Cash retail price: Compounded Tirzepatide $299/mo · Zepbound $1086/mo · Mounjaro $1135/mo. Compounded versions through telehealth typically run 60-80% less.

3-way comparison

Mounjaro vs Zepbound vs Compounded Tirzepatide

Side-by-side breakdown — efficacy, cost, regulatory status, and who each option fits best.

Mounjaro

tirzepatide

Zepbound

tirzepatide

Compounded Tirzepatide

tirzepatide (compounded)

Side-by-side comparison

Attribute	Mounjaro	Zepbound	Compounded Tirzepatide
Generic name	tirzepatide	tirzepatide	tirzepatide (compounded)
Drug class	—	—	—
Regulatory status	FDA approved	FDA approved	Compounded
Manufacturer	Eli Lilly	Eli Lilly	Various compounding pharmacies
Avg retail price	$1135/mo	$1086/mo	$299/mo
Without insurance	$1023–$1330/mo	$349–$1086/mo	$149–$399/mo
Savings card max	$25/mo	$25/mo	$0/mo

Mounjaro vs Zepbound vs Compounded Tirzepatide

Side-by-side comparison

FAQ

2-way head-to-heads

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