Loading content…
Affiliate-supportedIndependent editorialWe never sell medicationSee how
Geographic price comparison
Average monthly self-pay GLP-1 medication costs across all 50 states. Median $249/mo, range $205-$339/mo. Click any state on the map or in the tables below to see provider details and local Medicaid coverage.
Self-pay average across telehealth providers. Median $249/mo, range $205-$339/mo (n=50 states).
Averages reflect self-pay (no insurance) monthly costs across telehealth providers shipping to each state, plus retail pharmacy benchmarks. Real out-of-pocket varies by drug (Wegovy ~$499/mo on NovoCare, Zepbound $349-$499/mo on LillyDirect), insurance, and provider choice. Data scan: May 2026.
Tiers reflect the national distribution of self-pay averages. States in the low tier tend to have heavy compounded-provider activity; high-tier states reflect more retail pharmacy mix and stricter telehealth rules.
$200-$235/mes
$236-$285/mes
The same Wegovy or Zepbound prescription can cost dramatically different amounts depending on where you live — even with the same drug, same dose, and same manufacturer programs. Three factors drive the difference:
About 14 states require synchronous video consultation for new GLP-1 prescriptions; the rest permit asynchronous (chat / form-based) telehealth. Video-only states tend to have higher costs because fewer providers serve them and the consultation fee is higher.
States with comprehensive Medicaid GLP-1 coverage (California, Massachusetts, Pennsylvania, Virginia, Minnesota) generally see slightly higher self-pay averages — because the cheapest segment of the market is absorbed by Medicaid. States without Medicaid coverage (Arkansas, Mississippi, Idaho, Missouri) push more demand into the cheapest cash-pay tier, pulling the average down.
States with high obesity rates and lower household income (the Deep South, parts of Appalachia) have more active compounded-pharmacy advertising. Compounded semaglutide and tirzepatide cost $199-$349/mo — far below NovoCare ($499) or LillyDirect ($349-$499). When this segment dominates a state's mix, the average drops. Note: compounded GLP-1 are NOT FDA-approved as finished products. See our compounded GLP-1 buyer guide for safety considerations.
Sorted alphabetically. Click any state to see local providers, telehealth rules, and Medicaid coverage.
| State | Avg price | Tier |
|---|---|---|
| Alabama | $219/mo | Low |
| Alaska | $312/mo | High |
| Arizona | $249/mo | Mid |
| Arkansas | $209/mo | Low |
| California | $289/mo | High |
| Colorado | $295/mo | High |
| Connecticut | $325/mo | High |
| Delaware | $269/mo | Mid |
| Florida | $245/mo | Mid |
| Georgia | $232/mo | Low |
| Hawaii | $339/mo | High |
| Idaho | $234/mo | Low |
| Illinois | $289/mo | High |
| Indiana | $235/mo | Low |
| Iowa | $228/mo | Low |
| Kansas | $225/mo | Low |
| Kentucky | $222/mo | Low |
| Louisiana | $218/mo | Low |
| Maine | $279/mo | Mid |
| Maryland | $318/mo | High |
| Massachusetts | $335/mo | High |
| Michigan | $245/mo | Mid |
| Minnesota | $278/mo | Mid |
| Mississippi | $205/mo | Low |
| Missouri | $215/mo | Low |
| Montana | $254/mo | Mid |
| Nebraska | $232/mo | Low |
| Nevada | $269/mo | Mid |
| New Hampshire | $282/mo | Mid |
| New Jersey | $328/mo | High |
| New Mexico | $245/mo | Mid |
| New York | $339/mo | High |
| North Carolina | $238/mo | Mid |
| North Dakota | $242/mo | Mid |
| Ohio | $238/mo | Mid |
| Oklahoma | $219/mo | Low |
| Oregon | $298/mo | High |
| Pennsylvania | $285/mo | Mid |
| Rhode Island | $322/mo | High |
| South Carolina | $229/mo | Low |
| South Dakota | $232/mo | Low |
| Tennessee | $222/mo | Low |
| Texas | $238/mo | Mid |
| Utah | $268/mo | Mid |
| Vermont | $309/mo | High |
| Virginia | $269/mo | Mid |
| Washington | $308/mo | High |
| West Virginia | $209/mo | Low |
| Wisconsin | $245/mo | Mid |
| Wyoming | $251/mo | Mid |